UCLA researchers have devised a portable imaging system that can help diagnose gout that plagues eight million people in the United States. The system is new, small, and cost-effective, helping more primary care physicians screen for inflammatory arthritis, gout. The above research was published in the Science Report by the President of UCLA University, Professor of Electrical Engineering and Bioengineering, Aydogan Ozcan, Director of the California Institute of Nanotechnology, and John FitzGerald, Clinical Professor of UCLA Rheumatology. According to data from the Centers for Disease Control and Prevention (CDC), the incidence of gout in the United States today is three times that of 50 years ago. The cause of this phenomenon may be changes in Western diet, obesity and increased prevalence of hypertension. When gout occurs, the human blood uric acid level rises to uric acid crystals. Needle-like crystals are stored in joints, tendons, and ligaments, causing severe inflammation. The general disease is caused by a combination of factors such as diet, medication and genetics, and it is mostly caused by eating a lot of red meat (bovine and mutton), drinking a lot of beer and obesity. The doctor should first extract the joint fluid from the patient's joints, and then use the compensating polarized microscope to identify the uric acid crystals in the joint fluid sample, and finally diagnose the gout. However, recent studies have shown that primary care physicians generally do not diagnose gout through the above process. In addition, polarizing microscopes are bulky (about 9 kg), expensive ($10,000 - $20,000 or more), and have a relatively small field of view. It is time consuming to test large numbers of samples and the results are not reliable. Depending on the level of training, the inspector's ability to detect crystallization varies. The UCLA design platform uses a lensless on-chip microscope to design an imaging microscope that requires no lens and a large field of view. Holographic imaging was used to show the high-resolution crystalline material in the patient's joint fluid sampling - the symptoms of ventilation. The technique uses a polarizer to send a beam of light through a sample on a microscope slide to an image sensor microchip (which is also available in a cell phone camera or a network camera flash) and then through another polarizer. The image sensor captures the holographic diffraction pattern of the sample and feeds it into the computer to quickly generate a sample image. The platform utilizes the entire display area of ​​the image sensor microchip - approximately 20-30 square millimeters, which is 100 times the low resolution analysis of standard optical microscopes, enabling rapid analysis of large numbers of samples. “Our microscopes allow for the observation of larger sample areas, cost-effective, compact and lightweight, significantly improving the efficiency and accuracy of gout diagnosis, and even for resource-limited care and clinical applications,†Ozcan said. At present, traditional polarizing microscope is generally used to diagnose other body fluids such as kidney stones to form crystallization symptoms. UCLA technology is expected to eventually be used to diagnose the above diseases. Multifunctional Children's Study Table Chair Set Myopia in children is mostly caused by bad habits in the learning process, such as improper sitting posture and poor lighting. The learning environment created by a good learning table is still helpful for preventing myopia, so buy anti-myopia learning desks for children. There is still a certain effect, let children develop good study habits, which will accompany them for a lifetime.
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