Canadian pharmaceutical company develops new technology for using tobacco to produce flu vaccine

A Canadian pharmaceutical company successfully developed a new technology that uses tobacco plants to produce influenza vaccines, which greatly reduces the cycle and cost of vaccine production.

Since the 1940s, cultivating flu vaccines through chicken embryos has become the most mature and safe way recognized in the world.

Although this method is very safe and reliable, it takes hundreds of thousands or even millions of eggs in the vaccine production process, which consumes huge amounts. The production process takes up to 6 months, and sometimes it cannot respond to emergencies such as influenza outbreaks.

In order to solve the above problems, Canada's Medicago Pharmaceutical Company (Medicago) has invented a new technology for influenza vaccine production that takes less time and costs less: the Agrobacterium tumefaciens method will be used to carry the hemagglutinin gene for influenza virus. The plasmid was poured into the leaves of the mature tobacco plant Benshi tobacco, and the tobacco leaves were harvested after 4 to 5 days of cultivation in the greenhouse, and the virus-like particles were used as vaccines.

"It takes 6 months to culture the vaccine with chicken embryos, and it takes less than 2 months to use our method," said the company's CEO Chuck Shelton. The final price of vaccines produced using this method can be controlled below $ 1.

It is reported that the new technology of Modica Pharmaceuticals has completed clinical trials in Canada and the United States, respectively, and the safety and immunogenicity of the vaccine have been certified by the authoritative department. Soon, the company's plant in North Carolina will be put into commercial production.


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